Characterization of pediatric non-hematopoietic tumor metastases to the central nervous system: A single institution review

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  • CPCI-S
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作者: Newman, John;Leelatian, Nalin;Liang, Jiancong
通讯作者: Liang, JC
作者机构: Vanderbilt Univ, Med Ctr, Dept Pathol Microbiol & Immunol, Nashville, TN USA.
Vanderbilt Univ, Med Ctr, Dept Pathol Microbiol & Immunol, 11139 Doctors Off Tower,2200 Childrens Way, Nashville, TN 37232 USA.
通讯机构: Vanderbilt Univ, Med Ctr, Dept Pathol Microbiol & Immunol, 11139 Doctors Off Tower,2200 Childrens Way, Nashville, TN 37232 USA.
语种: 英文
关键词: CSF metastasis,Dura metastasis,Leptomeningeal metastasis,Mechanism of metastasis,Pediatric CNS metastasis,Pediatric neoplasms
期刊: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
ISSN: 0022-3069
年: 2024
卷: 82
期: 6
页码: 581-581
会议名称: 99th Annual Meeting of the American-Association-of-Neuropathologists (AAN)
会议时间: JUN 08-11, 2023
会议地点: Monterey, CA
摘要: Central nervous system (CNS) metastases represent a small portion of pediatric CNS neoplasms and data surrounding this condition with high morbidity is scarce. Single institutional archival institutional pathology records between 1999 and 2022 were searched for patients over 21 years old and younger with CNS, dura, cranial nerve, CSF, or leptomeningeal metastases; 41 cases were identified. We documented primary tumor types and locations, metastasis locations, types of invasion (direct extension vs distant metastasis), times from imaging or pathologic diagnosis to CNS involvement, and outcomes. Distant metastasis was the most common mechanism of metastasis (n = 32, 78%). I...

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